Halperin R, Ron-El R, Golan A, Hadas E, Schneider D, Bukovsky I, Herman A
Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel.
Hum Reprod. 1995 Apr;10(4):907-10. doi: 10.1093/oxfordjournals.humrep.a136059.
Uterine fluid samples from 109 patients undergoing in-vitro fertilization and embryo transfer were obtained so as to examine the relationship between the uterine fluid concentration of human decidua-associated protein (hDP) 200 and the implantation rate. The sampling was performed on the day of embryo transfer with a Wallace catheter, used for the testing of cervical patency before embryo replacement. The implantation rate, as well as the pregnancy rate, demonstrated a significantly positive correlation with the concentration of hDP 200 in the uterine fluid, measured just before embryo transfer. These results indicate that hDP 200, identified as a rheumatoid factor secreted by the endometrium, may be involved in the implantation process.
收集了109例接受体外受精和胚胎移植患者的子宫液样本，以研究人蜕膜相关蛋白（hDP）200的子宫液浓度与着床率之间的关系。采样在胚胎移植当天进行，使用华莱士导管，该导管在胚胎植入前用于检测宫颈通畅情况。着床率以及妊娠率与胚胎移植前即刻测量的子宫液中hDP 200的浓度呈显著正相关。这些结果表明，被鉴定为子宫内膜分泌的类风湿因子的hDP 200可能参与着床过程。
