Zhu K J, Zhu T C
Department of Dermatology, Second Affiliated Hospital of Zhejiang Medical University, Hangzhou, P.R. of China.
J Dermatol. 1995 Jun;22(6):419-23.
Epidermal cellular DNA content was detected by flow cytometry on 14 samples of normal skin and both lesional and nonlesional areas of 36 patients with psoriasis vulgaris. The results showed that the proliferative activity of epidermal cells increased in nonlesions and even more in lesions of patients from the levels in normal skin. These differences were significant (p < 0.05). Clinical features and histopathological changes were observed, and self comparisons of 6 patients before and after treatment were also done. The clinical significance of these changes was discussed.
采用流式细胞术检测了14例正常皮肤样本以及36例寻常型银屑病患者皮损和非皮损部位的表皮细胞DNA含量。结果显示，与正常皮肤水平相比，患者非皮损部位表皮细胞的增殖活性增加，皮损部位增加更明显。这些差异具有统计学意义（p < 0.05）。观察了临床特征和组织病理学变化，并对6例患者治疗前后进行了自身对照。对这些变化的临床意义进行了讨论。
