Boros S J, Reynolds J W
Clin Pediatr (Phila). 1976 Feb;15(2):123-34. doi: 10.1177/000992287601500203.
Five premature infants experiencing frequent episodes of apnea and bradycardia were treated with continuous positive airway pressure delivered by nasopharyngeal tube. A significant decrease in the frequency and severity of apneic spells was observed. Premature withdrawal from end expiratory pressure resulted in an increase in both the incidence and the duration of the apneic episodes. We suggest that hypoventilation and a reduced functional residual capacity (FRC) are related to the development of prolonged apnea. Expansion and stablization of FRC with small amounts of end expiratory pressure appears to be beneficial.
五名经常出现呼吸暂停和心动过缓的早产儿接受了经鼻咽管持续气道正压通气治疗。观察到呼吸暂停发作的频率和严重程度显著降低。过早撤去呼气末正压导致呼吸暂停发作的发生率和持续时间均增加。我们认为，通气不足和功能残气量（FRC）降低与长时间呼吸暂停的发生有关。用少量呼气末正压来扩张和稳定功能残气量似乎是有益的。
