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剖宫产相关出血:何时需要输血?

Hemorrhage associated with cesarean delivery: when is transfusion needed?

作者信息

Naef R W, Washburne J F, Martin R W, Magann E F, Scanlon P H, Morrison J C

机构信息

Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.

出版信息

J Perinatol. 1995 Jan-Feb;15(1):32-5.

PMID:7650550
Abstract

Our objective was to determine the incidence of blood administration after cesarean delivery and whether such transfusions are always beneficial. In this retrospective study 1610 women underwent cesarean delivery during a 2-year period and 127 of these patients had hemorrhage during or after operation. Of these subjects 103 received blood because of intraoperative hemorrhage, a reduction in the hematocrit of more than 10 points, or because the postoperative hematocrit was < 24%. These subjects were compared with the remaining women (n = 24) who met the same criteria for hemorrhage but did not receive transfusion. The maternal age, race, and parity were similar in both groups. The estimated blood loss (873 +/- 484 ml) and the preoperative hematocrit (33.4% +/- 6.4%) in the women who did not receive transfusion were not significantly different from those of patients who received packed red blood cells (854 +/- 576 ml and 30.0% +/- 5.4%, respectively). The postdelivery hematocrit was similar in both groups: 25.9% +/- 4.3% in the nontransfused group and 24.5% +/- 5.6% in the transfused group. Patients in the transfused group received a mean of 3.8 +/- 4.9 units of packed red blood cells, with a range of 1 to 40 units. The mean equilibrated (stable) hematocrit after transfusion was 28.4% +/- 5.4%, which was significantly greater than the mean equilibrated postoperative hematocrit of 22.7% +/- 4.6% in patients who did not receive transfusion (p < 0.0001). Nonetheless, the hospital stay, incidence of postoperative infection, and incidence of wound complications were similar in the two groups.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们的目的是确定剖宫产术后输血的发生率,以及这种输血是否总是有益的。在这项回顾性研究中,1610名女性在两年期间接受了剖宫产,其中127名患者在手术期间或术后出现出血。在这些受试者中,103人因术中出血、血细胞比容降低超过10个百分点或术后血细胞比容<24%而接受输血。将这些受试者与其余24名符合相同出血标准但未接受输血的女性进行比较。两组的产妇年龄、种族和产次相似。未接受输血的女性估计失血量(873±484ml)和术前血细胞比容(33.4%±6.4%)与接受浓缩红细胞输血的患者(分别为854±576ml和30.0%±5.4%)无显著差异。两组产后血细胞比容相似:未输血组为25.9%±4.3%,输血组为24.5%±5.6%。输血组患者平均接受3.8±4.9单位浓缩红细胞,范围为1至40单位。输血后平均平衡(稳定)血细胞比容为28.4%±5.4%,显著高于未接受输血患者术后平均平衡血细胞比容22.7%±4.6%(p<0.0001)。尽管如此,两组的住院时间、术后感染发生率和伤口并发症发生率相似。(摘要截断于250字)

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