Fong Jill, Gurewitsch Edith D, Kang Hey-Joo, Kump Lisa, Mack Patricia Fogarty
Department of Anesthesiology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, NY 10021, USA.
Anesth Analg. 2007 Mar;104(3):666-72. doi: 10.1213/01.ane.0000253232.45403.e5.
We sought to determine to what extent intraoperative salvaged red blood cells (RBC) might theoretically reduce exposure to appropriately transfused allogenic erythrocytes in Cesarean delivery patients.
Medical records of Cesarean delivery patients requiring blood transfusions from January 1, 1992 to June 30, 1996 and June 1, 1998 to June 30, 2003 were reviewed. For each patient, we calculated the number of allogenic RBC units that could have theoretically been avoided had intraoperative autotransfusion been performed, based upon estimated blood loss, preoperative hematocrit, and the amount of retrieved blood needed to yield a single RBC unit. RBC transfusion appropriateness was determined using the recommended guideline of transfusing RBCs if the hemoglobin is <7 gm/dL in a patient with continuing bleeding.
A small percentage of Cesarean delivery patients (1.8%) received blood product transfusions. Of 207 patients receiving blood transfusions, salvaged erythrocytes could have theoretically decreased exposure to allogenic RBCs in 115 (55.6%) patients. Only 75.7% of these 115 patients were appropriately transfused with erythrocytes.
Theoretically, based on best, average, and worst RBC salvage recovery calculations, 25.1%, 21.2%, or 14.5% of the appropriately transfused patients, respectively, could have completely avoided allogenic RBC transfusion.
我们试图确定剖宫产患者术中回收的红细胞(RBC)在理论上能在多大程度上减少异体红细胞的合理输注暴露。
回顾了1992年1月1日至1996年6月30日以及1998年6月1日至2003年6月30日期间需要输血的剖宫产患者的病历。对于每位患者,我们根据估计失血量、术前血细胞比容以及获得一个红细胞单位所需回收的血量,计算了如果进行术中自体输血理论上可避免的异体红细胞单位数量。红细胞输注的合理性根据推荐指南确定,即对于持续出血且血红蛋白<7g/dL的患者输注红细胞。
一小部分剖宫产患者(1.8%)接受了血液制品输注。在207例接受输血的患者中,回收的红细胞理论上可减少115例(55.6%)患者的异体红细胞暴露。这115例患者中只有75.7%接受了合适的红细胞输注。
理论上,基于最佳、平均和最差的红细胞回收计算,分别有25.1%、21.2%或14.5%的合适输注患者可以完全避免异体红细胞输血。