Shimizu M T, Jorge A O, Unterkircher C S, Fantinato V, Paula C R
School of Dentistry, Department of Pathology, UNESP, Brazil.
J Med Vet Mycol. 1995 Jan-Feb;33(1):27-31.
The production of hyaluronidase and chondroitin sulphatase by Candida albicans, Candida tropicalis, Candida parapsilosis, Candida guilliermondii and Candida krusei was investigated using a complex culture medium (Sabouraud glucose agar) and a chemically defined medium. Among the 63 C. albicans isolates tested, 61 (97.8%) were found to be hyaluronidase and chondroitin sulphatase producers; one isolate produced only chondroitin sulphatase and one other was unable to produce either enzyme. The second major hyaluronidase and chondroitin sulphatase producing species was C. tropicalis followed by C. guilliermondii, C. parapsilosis and C. krusei. Among the C. albicans isolates tested no relation between the source of isolation and the amount of hyaluronidase and chondroitin sulphatase produced was found.
使用复杂培养基（沙氏葡萄糖琼脂）和化学成分确定的培养基，对白色念珠菌、热带念珠菌、近平滑念珠菌、季也蒙念珠菌和克柔念珠菌产生透明质酸酶和硫酸软骨素酶的情况进行了研究。在所测试的63株白色念珠菌分离株中，发现61株（97.8%）能产生透明质酸酶和硫酸软骨素酶；一株分离株仅产生硫酸软骨素酶，另一株则无法产生这两种酶。第二大产生透明质酸酶和硫酸软骨素酶的菌种是热带念珠菌，其次是季也蒙念珠菌、近平滑念珠菌和克柔念珠菌。在所测试的白色念珠菌分离株中，未发现分离来源与所产生的透明质酸酶和硫酸软骨素酶量之间存在关联。
