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一种用于验证药物注入大鼠脑室系统的快速方法。

A rapid method for the verification of drug injection into the cerebral ventricular system of the rat.

作者信息

Hernandez A, Ruiz S, Paeile C

出版信息

Experientia. 1975 Dec 15;31(12):1475-6. doi: 10.1007/BF01923252.

DOI:10.1007/BF01923252
PMID:765141
Abstract

A precise method for the injection of drugs into the cerebroventricular system of small animals used for experimentation is described. This method, based on the intraventricular pressue record, gives absolute certainty for the injection of a drug into a previously selected site and thus avoids the subsequent histological studies.

摘要

描述了一种向用于实验的小动物脑室系统注射药物的精确方法。该方法基于脑室内压力记录，能绝对确定将药物注射到预先选定的部位，从而避免了后续的组织学研究。

相似文献

1
A rapid method for the verification of drug injection into the cerebral ventricular system of the rat.一种用于验证药物注入大鼠脑室系统的快速方法。
Experientia. 1975 Dec 15;31(12):1475-6. doi: 10.1007/BF01923252.
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A reliable technique for midline stereotaxic cannulation of the third ventricle in the rat.一种用于大鼠第三脑室中线立体定向插管的可靠技术。
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CT-guided stereotactic placement of ventricular cannula.CT引导下脑室套管的立体定向放置。
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Increasing the effectiveness of intracerebral injections in adult and neonatal mice: a neurosurgical point of view.从神经外科角度提高成年和新生小鼠脑内注射的有效性
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Proceedings: Combined EEG recording and intraventricular administration of drugs in the conscious rat.论文集：清醒大鼠的脑电图联合记录与脑室内给药
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[A simple and rapid method for implantation of metal cannulas into the rat brain ventricular system].
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Stereotaxic implantation of cannulae for subsequent drug administration into the third ventricles of conscious mice [proceedings].用于向清醒小鼠第三脑室后续给药的套管的立体定向植入[会议记录]
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引用本文的文献

1
A simple method for the verification of a successful cannulation of the rat cerebral ventricles.一种验证大鼠脑室插管成功的简单方法。
Experientia. 1980 Jul 15;36(7):887-9. doi: 10.1007/BF01978633.

本文引用的文献

1
METABOLISM OF (H3)NOREPINEPHRINE IN THE RAT BRAIN.大鼠脑中（H3）去甲肾上腺素的代谢
J Neurochem. 1965 Jan;12:25-30. doi: 10.1111/j.1471-4159.1965.tb10247.x.
2
Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.清醒小鼠脑内注射药物所产生的药理效应。
Br J Pharmacol Chemother. 1957 Mar;12(1):12-5. doi: 10.1111/j.1476-5381.1957.tb01354.x.
3
A permanent cannula for intraventricular injections in cats.一种用于猫脑室内注射的永久性套管。
J Physiol. 1953 Apr 28;120(1-2):3P-5P.
4
A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain.一种将H3-去甲肾上腺素注入大鼠脑侧脑室的简单快速方法。
Life Sci. 1967 Feb 1;6(3):281-91. doi: 10.1016/0024-3205(67)90157-9.
5
The effects of pentobarbital on the fate of intracisternally administered norepinephrine-H3.戊巴比妥对脑池内注射去甲肾上腺素-H3 命运的影响。
J Pharmacol Exp Ther. 1967 Aug;157(2):311-8.
6
The metabolism of tritiated dopamine in regions of the rat brain in vivo. I. The separation of catecholamines and their metabolites.体内大鼠脑区中氚标记多巴胺的代谢。I. 儿茶酚胺及其代谢产物的分离。
J Neurochem. 1969 Sep;16(9):1361-6. doi: 10.1111/j.1471-4159.1969.tb05987.x.
7
Interaction between morphine and morphine antagonists after systemic and intraventricular application.全身及脑室内给药后吗啡与吗啡拮抗剂之间的相互作用。
Eur J Pharmacol. 1970 Sep 1;12(1):53-64. doi: 10.1016/0014-2999(70)90028-2.
8
Volumetric compartmentalization of the cranial cerebrospinal fluid system determined radiographically in the cat.通过影像学方法确定猫颅骨脑脊液系统的容积分区。
Anat Rec. 1966 Jul;155(3):305-13. doi: 10.1002/ar.1091550304.
9
The fate of intracisternally administered norepinephrine-3H in the brain and spinal cord of the rabbit.脑池内注射的3H-去甲肾上腺素在兔脑和脊髓中的命运。
J Pharmacol Exp Ther. 1971 Jul;178(1):8-19.