McDuffee A T, Tobias J D
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2591, USA.
Pediatr Emerg Care. 1995 Jun;11(3):186-7. doi: 10.1097/00006565-199506000-00013.
Flumazenil is a benzodiazepine receptor antagonist used to reverse sedation and respiratory depression induced by benzodiazepines. Seizures and cardiac arrhythmias have complicated its use in adult patients. Overdose patients who have coingested tricyclic antidepressants have a higher risk of these complications. Little information exists concerning adverse effects of flumazenil in children. We report the occurrence of a generalized tonic-clonic seizure in a pediatric patient following the administration of flumazenil.
