DiBattista D
Psychology Department, Brock University, St. Catharines, Ontario, Canada.
Physiol Behav. 1995 Jun;57(6):1127-9. doi: 10.1016/0031-9384(95)00020-j.
Golden hamsters underwent either surgical removal of the pregastric pouch (PGX) or sham surgery. Following recovery from surgery, hamsters were given free access to 15% (v/v) ethanol solution for 40 days, and then to 30% ethanol solution for a further 32 days. PGX and sham-operated hamsters ingested similar amounts of absolute ethanol throughout the study, with intake exceeding 15 g/kg/day when 30% ethanol solution was available. The failure to find a significant effect of surgical treatment on ethanol intake was not attributable to a lack of statistical power, but rather suggests that other factors, such as the hamster's high levels of hepatic alcohol dehydrogenase, are responsible for the hamster's unusual tolerance for ethanol.
金黄仓鼠接受了胃前袋手术切除（PGX）或假手术。手术后恢复期间，仓鼠可自由饮用15%（v/v）乙醇溶液40天，然后再饮用30%乙醇溶液32天。在整个研究过程中，接受PGX手术和假手术的仓鼠摄入的纯乙醇量相似，当有30%乙醇溶液时，摄入量超过15克/千克/天。手术治疗对乙醇摄入量未产生显著影响，这并非归因于统计效力不足，而是表明其他因素，如仓鼠体内高水平的肝醇脱氢酶，是仓鼠对乙醇具有异常耐受性的原因。
