DiBattista D, Robillard M
Psychology Department, Brock University, St. Catharines, Ontario, Canada.
Physiol Behav. 1993 Mar;53(3):425-9. doi: 10.1016/0031-9384(93)90134-2.
Unlike other adult mammals, golden hamsters voluntarily consume substantial amounts of the disaccharide sugar lactose. It was hypothesized that the hamster's readiness to consume lactose depends upon its possession of a pregastric pouch in which ingested lactose is broken down into its constituent monosaccharides, thus preventing the aversive gastrointestinal symptoms that monogastric animals experience following lactose ingestion. Adult golden hamsters underwent either surgical removal of the pregastric pouch or sham surgery. Following recovery from surgery, hamsters were given continuous free access for 14 days to tap water, Purina Rodent Chow, a 24% sugar solution (either lactose or sucrose), and a Purina chow-based diet containing 30% added sugar (for each hamster, the same sugar that was provided in solution). Surgical removal of the pregastric pouch caused a 40% reduction in total lactose consumption: this reduction resulted from equivalent decreases in consumption of the lactose solution and the lactose-containing diet. Pouch removal had no effect on total sucrose consumption, and sham surgery had no effect on either lactose or sucrose consumption. These results support the conclusion that the adult hamster's unusually high level of voluntary lactose consumption depends upon its possession of a pregastric pouch, which plays an important role in lactose digestion.
与其他成年哺乳动物不同，金黄仓鼠会主动大量摄取二糖乳糖。据推测，仓鼠愿意摄取乳糖取决于其拥有一个胃前袋，摄入的乳糖在其中被分解为单糖成分，从而避免了单胃动物摄入乳糖后出现的胃肠道不适症状。成年金黄仓鼠接受了胃前袋切除手术或假手术。术后恢复后，仓鼠可连续14天自由获取自来水、普瑞纳啮齿动物饲料、24%的糖溶液（乳糖或蔗糖）以及添加了30%糖的普瑞纳饲料（每只仓鼠所喂的糖与溶液中提供的糖相同）。胃前袋切除手术使乳糖总摄入量减少了40%：这种减少是由于乳糖溶液和含乳糖饲料的摄入量同等减少所致。切除胃前袋对蔗糖总摄入量没有影响，假手术对乳糖或蔗糖摄入量也没有影响。这些结果支持了这样的结论，即成年仓鼠异常高的乳糖主动摄入量取决于其拥有胃前袋，胃前袋在乳糖消化中起重要作用。
