Chan K
School of Pharmacy, Liverpool John Moores University, UK.
Trends Pharmacol Sci. 1995 Jun;16(6):182-7. doi: 10.1016/s0165-6147(00)89019-7.
Recently, traditional chinese medicine (TCM) natural products have been used to produce impressive responses in atopic eczema and related dermatological disorders that have proved resistant to orthodox treatments. The increasing popularity of TCM natural products has also produced fear about their toxicity and uncertainty about their ingredients. In the western world, very little is known of the efficacy and safety of TCM, and the legal responsibilities of practitioners are undefined. In this article Kelvin Chan overviews the TCM practitioners' concepts of how TCM natural products work and attempts to suggest the pharmacological interpretation of their mechanisms of action. The future of TCM is discussed by critically assessing the authenticity, quality, toxicity and clinical efficacy of these natural products.
最近，中药天然产物已被用于治疗特应性皮炎及相关皮肤病，这些疾病对传统治疗方法已产生抗药性，而中药天然产物却能产生显著疗效。中药天然产物越来越受欢迎，这也引发了人们对其毒性的担忧以及对其成分的不确定性。在西方世界，人们对中药的功效和安全性知之甚少，而且从业者的法律责任也不明确。在本文中，陈凯文概述了中医从业者对中药天然产物作用方式的概念，并试图对其作用机制进行药理学解释。通过严格评估这些天然产物的真实性、质量、毒性和临床疗效，探讨了中药的未来。
