Clauw D J
Georgetown University School of Medicine, Washington, D.C., USA.
Am Fam Physician. 1995 Sep 1;52(3):843-51, 853-4.
Fibromyalgia is a common condition characterized by diffuse musculoskeletal pain and fatigue. The syndrome is defined by the presence of musculoskeletal tender points on physical examination. Additionally, persons with this syndrome have a high incidence of headaches, ocular and vestibular complaints, paresthesias, esophageal dysmotility, "allergic" symptoms, irritable bowl syndrome, genitourinary symptoms and affective disorders. Recent research has revealed a number of objective biochemical, hormonal and neurotransmitter abnormalities associated with fibromyalgia, making it a clearly identifiable condition. These abnormalities may clarify our understanding of the pathogenesis and treatment of fibromyalgia.
纤维肌痛是一种常见病症，其特征为弥漫性肌肉骨骼疼痛和疲劳。该综合征通过体格检查时肌肉骨骼压痛点的存在来定义。此外，患有这种综合征的人头痛、眼部和前庭不适、感觉异常、食管运动障碍、“过敏”症状、肠易激综合征、泌尿生殖系统症状及情感障碍的发生率较高。最近的研究揭示了一些与纤维肌痛相关的客观生化、激素和神经递质异常，使其成为一种可明确识别的病症。这些异常可能会阐明我们对纤维肌痛发病机制和治疗的理解。
