Schwentker E P, Gibson D A
J Bone Joint Surg Am. 1976 Jan;58(1):32-8.
To clarify the role of the orthopaedic surgeon in the management of spinal muscular atrophy, the records of 130 patients were reviewed. Seventy-three had died. Of the remaining fifty-seven, fifty were re-examined. The clinical manifestations of the disease, particularly those giving rise to orthopaedic problems, were studied. At the time of review the average age of the patients was 11.5 years. Thirty-five could not walk and all had some degree of muscle weakness, more marked proximally and in the lower limbs. The most common medical problem was repeated respiratory infection and the major orthopaedic problem was scoliosis, often severe. Nine of the thirty-five patients with scoliosis had had spine fusion. Most of them suffered some functional loss in attaining spinal stability.
为了阐明骨科医生在脊髓性肌萎缩症治疗中的作用，我们回顾了130例患者的病历。其中73例已经死亡。在其余的57例中，50例接受了复查。对该疾病的临床表现，尤其是那些引发骨科问题的表现进行了研究。在复查时，患者的平均年龄为11.5岁。35例患者不能行走，且均有一定程度的肌无力，近端和下肢更为明显。最常见的内科问题是反复呼吸道感染，主要的骨科问题是脊柱侧凸，通常较为严重。35例脊柱侧凸患者中有9例接受了脊柱融合术。他们中的大多数在实现脊柱稳定方面出现了一些功能丧失。
