Piasecki J O, Mahinpour S, Levine D B
Clin Orthop Relat Res. 1986 Jun(207):44-54.
From 1966 to 1983, 11 females and eight males with spinal muscular atrophy were treated by arthrodesis. Seventeen of 19 patients were evaluated by follow-up physical examination, roentgenograms, and questionnaires. In order to compare long-term versus short-term results, changes in management, and factors contributing to morbidity and mortality, three groups were identified for study. Group I consisted of 11 patients operated between 1966 and 1983 and alive at follow-up evaluation. Group II consisted of five patients operated between 1980 and 1983. Group III consisted of three patients, all deceased at follow-up evaluation and operated before 1980. In Group I, the preoperative curve averaged 119 degrees and at final follow-up examination, 99 degrees. The average preoperative curve in Group II was 80 degrees and at follow-up examination, 49 degrees. Long-term follow-up vital capacities were obtained in nine patients. The average preoperative vital capacity was 1033 cm3, and the average vital capacity seven years postoperation was 860 cm3. Most patients reported improvement in sitting, balance, and comfort. All patients are wheelchair-bound, as they were before surgery. Few long-term respiratory problems were reported.
1966年至1983年期间，对11名女性和8名男性脊髓性肌萎缩症患者进行了关节固定术治疗。19例患者中的17例通过随访体格检查、X线片和问卷调查进行了评估。为了比较长期与短期结果、治疗方法的变化以及导致发病和死亡的因素，确定了三组进行研究。第一组包括11例在1966年至1983年期间接受手术且在随访评估时仍存活的患者。第二组包括5例在1980年至1983年期间接受手术的患者。第三组包括3例患者，均在随访评估时死亡且于1980年前接受手术。在第一组中，术前侧弯平均为119度，在最终随访检查时为99度。第二组术前侧弯平均为80度，随访检查时为49度。对9例患者进行了长期随访肺活量测定。术前平均肺活量为1033立方厘米，术后七年平均肺活量为860立方厘米。大多数患者报告在坐姿、平衡和舒适度方面有所改善。所有患者仍需依赖轮椅，与手术前一样。报告的长期呼吸问题较少。
