Iureneva S V, Smetnik V P
Akush Ginekol (Mosk). 1995(3):41-4.
Eighty-eight women subjected to total oophorectomy for benign tumors and tumor-like formations in the uterus and tubes were examined. The mean age of the patients was 33.3 +/- 2.4 years. Bone tissue status was assessed by monophoton absorptiometry and computer-aided tomography. A negligible reduction of mineral density of osseous tissue was observed early after oophorectomy, its annual loss being high. In later periods after surgery, vice versa, a more expressed reduction of bone density and a relatively low rate of its annual reduction were observed. Specific features of the processes of osteoporosis in various periods after surgical removal of the ovaries make substitution hormonal therapy advisable for oophorectomized patients in the early periods after surgery, in order to effectively prevent and treat osteoporosis.
对88名因子宫和输卵管良性肿瘤及肿瘤样病变而接受全卵巢切除术的女性进行了检查。患者的平均年龄为33.3±2.4岁。通过单光子吸收法和计算机断层扫描评估骨组织状况。卵巢切除术后早期观察到骨组织矿物质密度有轻微降低,其年流失率较高。而在术后后期,情况则相反,观察到骨密度降低更为明显,但其年降低率相对较低。卵巢切除术后不同时期骨质疏松过程的具体特征表明,为有效预防和治疗骨质疏松,对卵巢切除术后早期的患者进行替代激素治疗是可取的。