Handfield-Jones S E, Jenkins R E, Whittaker S J, Besse C P, McGibbon D H
St John's Dermatology Centre, St Thomas' Hospital, London, U.K.
Br J Dermatol. 1993 Aug;129(2):175-7. doi: 10.1111/j.1365-2133.1993.tb03523.x.
Anticonvulsants can cause a characteristic hypersensitivity reaction. This multisystem reaction typically presents as fever, mucocutaneous eruptions, lymphadenopathy and hepatitis. There is cross-reactivity between different anticonvulsants, which complicates subsequent therapy. We report three cases to illustrate both the typical features, and less common complications, of this under-recognized and life-threatening syndrome.
抗惊厥药可引起一种特征性的过敏反应。这种多系统反应通常表现为发热、皮肤黏膜疹、淋巴结病和肝炎。不同抗惊厥药之间存在交叉反应，这使得后续治疗变得复杂。我们报告三例病例，以说明这种未得到充分认识且危及生命的综合征的典型特征和较少见的并发症。
