Thalén B E, Kjellman B F, Mørkrid L, Wetterberg L
Karolinska Institute, Department of Psychiatry, St. Göran's Hospital, Stockholm, Sweden.
Eur Arch Psychiatry Clin Neurosci. 1995;245(2):101-8. doi: 10.1007/BF02190736.
This study compares the clinical characteristics of 127 patients with major depression, 99 with a seasonal and 28 with a non-seasonal pattern. Non-seasonal depressives had significantly higher scores in the Comprehensive Psychopathological Rating Scale, and the Hamilton Depression Rating Scale. Increased appetite and carbohydrate craving, were more frequently reported among patients with a seasonal pattern. Compared to previous reports, the Swedish patients with seasonal depression had less atypical vegetative symptomatology. The symptoms sadness, suicidal thoughts, slowness of movement, gastrointestinal symptoms, and weight loss were more frequent in the patients with a non-seasonal pattern. The clinical symptomatology has a low specificity compared to the seasonal pattern in diagnosing seasonal affective disorder according to DSM-III-R for seasonal and non-seasonal patterns.
本研究比较了127例重度抑郁症患者的临床特征,其中99例为季节性模式,28例为非季节性模式。非季节性抑郁症患者在综合精神病理学评定量表和汉密尔顿抑郁评定量表上的得分显著更高。食欲增加和对碳水化合物的渴望在季节性模式患者中报告得更为频繁。与之前的报告相比,瑞典季节性抑郁症患者的非典型植物神经症状较少。悲伤、自杀念头、行动迟缓、胃肠道症状和体重减轻等症状在非季节性模式患者中更为常见。根据DSM-III-R中季节性和非季节性模式的标准,在诊断季节性情感障碍时,临床症状学与季节性模式相比特异性较低。