Rosenthal N E, Sack D A, Gillin J C, Lewy A J, Goodwin F K, Davenport Y, Mueller P S, Newsome D A, Wehr T A
Arch Gen Psychiatry. 1984 Jan;41(1):72-80. doi: 10.1001/archpsyc.1984.01790120076010.
Seasonal affective disorder (SAD) is a syndrome characterized by recurrent depressions that occur annually at the same time each year. We describe 29 patients with SAD; most of them had a bipolar affective disorder, especially bipolar II, and their depressions were generally characterized by hypersomnia, overeating, and carbohydrate craving and seemed to respond to changes in climate and latitude. Sleep recordings in nine depressed patients confirmed the presence of hypersomnia and showed increased sleep latency and reduced slow-wave (delta) sleep. Preliminary studies in 11 patients suggest that extending the photoperiod with bright artificial light has an antidepressant effect.
季节性情感障碍(SAD)是一种以每年同一时间反复出现抑郁发作为特征的综合征。我们描述了29例季节性情感障碍患者;他们中的大多数患有双相情感障碍,尤其是双相II型,其抑郁通常表现为嗜睡、暴饮暴食和对碳水化合物的渴望,并且似乎对气候和纬度的变化有反应。对9例抑郁患者的睡眠记录证实了嗜睡的存在,并显示睡眠潜伏期延长和慢波(δ)睡眠减少。对11例患者的初步研究表明,用明亮的人造光延长光照周期具有抗抑郁作用。