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[巴塞罗那省13家综合医院的菌血症。1674例病例的前瞻性研究。加泰罗尼亚县医院微生物学家小组]

[Bacteremia in 13 general hospitals of the province of Barcelona. Prospective study of 1,674 episodes. Group of Microbiologists of the County Hospitals of Catalonia].

作者信息

Matas L, Martí C, Morera M A, Sierra M, Vilamala A, Corcoy F

机构信息

Hospital de Sabadell.

出版信息

Enferm Infecc Microbiol Clin. 1995 Jun-Jul;13(6):345-55.

PMID:7654835
Abstract

BACKGROUND

Clinical and microbiological description of bacteremias seen in 13 regional hospitals of Barcelona.

METHODS

From January to December of 1991 a multicenter prospective study of bacteremia in regional hospitals was performed. The filiation, clinical findings and microbiological results were registered according to a common protocol.

RESULTS

We studied 1674 episodes of bacteremia (13.8 per 1000 admissions). Patients were distributed into 3 groups according to age: under 14: 204 patients, between 14 to 65: 759 and over 65: 711 patients. Men account for 55% and women for 45% of episodes. The bacteremia was hospital-acquired in 24.4% of cases. The most common foci of infection were: urinary tract (32%), respiratory tract (14%), intestinal tract (8%), intravascular catheter (7%), biliary tract (7%) and unknown (10%). The most commonly isolated strains were: Escherichia coli 544 cases, Streptococcus pneumoniae 212, Staphylococcus aureus 139, coagulase negative staphylococi 85, Non-typhoid Salmonella 66, Neisseria meningitidis 63, Pseudomonas sp. 59, Enterococcus sp. 59 and Bacteroides sp. 58. Polimicrobial bacteremia was detected in 83 episodes (5%). Related mortality rate was 9.6% (161 patients).

摘要

背景

巴塞罗那13家地区医院菌血症的临床及微生物学描述。

方法

1991年1月至12月,在地区医院开展了一项关于菌血症的多中心前瞻性研究。按照通用方案记录谱系、临床发现及微生物学结果。

结果

我们研究了1674例菌血症病例(每1000例入院患者中有13.8例)。患者按年龄分为3组:14岁以下:204例患者;14至65岁:759例;65岁以上:711例。菌血症发作病例中男性占55%,女性占45%。24.4%的病例菌血症为医院获得性。最常见的感染部位为:泌尿系统(32%)、呼吸道(14%)、肠道(8%)、血管内导管(7%)、胆道(7%)及不明部位(10%)。最常分离出的菌株为:大肠杆菌544例、肺炎链球菌212例、金黄色葡萄球菌139例、凝固酶阴性葡萄球菌85例、非伤寒沙门菌66例、脑膜炎奈瑟菌63例、假单胞菌属59例、肠球菌属59例及拟杆菌属58例。83例(5%)检测到多菌型菌血症。相关死亡率为9.6%(161例患者)。

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