Sabater S, Moreno R
Laboratorio de Microbiologia, Hospital General de Castellon, Castellon, Espana.
Rev Esp Quimioter. 2008 Dec;21(4):217-23.
The aim of this study was to know the frequency of bacteremias produced by Staphylococcus aureus and the sensibility that strains showed, as well as the clinical characteristics of the patients.
We retrospectively studied cases of S. aureus bacteremia detected in our hospital from 2001 to 2005 and also reviewed medical histories from patients during 2005.
A total of 295 cases of S. aureus bacteremia were detected in this study. Annual distributions of the cases were as follows: 35, 54, 62, 64 and 80. By gender, 62.7 % related to males and 37.3 % to females. A total of 58.6 % of the patients were admitted to medical services and 49 % were older than 65 years. Regarding resistance, 34 % of the strains showed resistance to oxacillin, 33 % to ciprofloxacin, 41 % to erythromycin and 4.4 % to gentamicin. In one-third of the patients, S. aureus was isolated in other samples, the catheter being the most common. A total of the 73.5 % of the patients had some baseline disease and the most frequent predisposing factor was the intravascular catheter. The bacteremias were nosocomial-acquired in 73.5 % of the cases.
In our hospital, S. aureus bacteremia and oxacillin resistance has been increasing over the years of this study.
本研究旨在了解金黄色葡萄球菌引起的菌血症的发生频率、菌株的敏感性以及患者的临床特征。
我们回顾性研究了2001年至2005年在我院检测到的金黄色葡萄球菌菌血症病例，并查阅了2005年患者的病史。
本研究共检测到295例金黄色葡萄球菌菌血症病例。病例的年度分布如下：35例、54例、62例、64例和80例。按性别划分，男性占62.7%，女性占37.3%。共有58.6%的患者入住内科，49%的患者年龄超过65岁。关于耐药性，34%的菌株对苯唑西林耐药，33%对环丙沙星耐药，41%对红霉素耐药，4.4%对庆大霉素耐药。三分之一的患者在其他样本中分离出金黄色葡萄球菌，其中导管是最常见的样本。共有73.5%的患者患有某种基础疾病，最常见的诱发因素是血管内导管。73.5%的病例为医院获得性菌血症。
在本研究的几年中，我院金黄色葡萄球菌菌血症和苯唑西林耐药性一直在增加。
