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Chemoattractant signaling and leukocyte activation.

作者信息

Bokoch G M

机构信息

Department of Immunology, Scripps Research Institute, La Jolla, CA 92037, USA.

出版信息

Blood. 1995 Sep 1;86(5):1649-60.

PMID:7654998
Abstract
摘要

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Chemoattractant signaling and leukocyte activation.
Blood. 1995 Sep 1;86(5):1649-60.
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Leukocyte activation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism.趋化因子受体介导的白细胞激活:鸟嘌呤核苷酸调节蛋白和多磷酸肌醇代谢的作用
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Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity.趋化肽诱导的人中性粒细胞中Ras激活与p120-GAP活性的抑制相关。
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Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.环磷酸腺苷增加剂通过抑制磷脂酰肌醇3激酶而非受体介导的钙离子内流来干扰趋化因子诱导的中性粒细胞呼吸爆发。
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J Biol Chem. 1997 Jan 10;272(2):937-44. doi: 10.1074/jbc.272.2.937.

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