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原发性心脏瓣膜肿瘤。

Primary cardiac valve tumors.

作者信息

Ryan P E, Obeid A I, Parker F B

机构信息

Suny Health Science Center, Syracuse Crouse Irving Memorial Hospital, NY, USA.

出版信息

J Heart Valve Dis. 1995 May;4(3):222-6.

PMID:7655679
Abstract

Cardiac valve tumors are rare, but may have significant clinical manifestations. We report three cases of mitral valve tumor successfully treated by surgical excision. Two out of three patients presented with neurologic symptoms, and by utilizing echocardiography the valvular lesions were discovered. Surgical removal with preservation of normal valve tissue and function was accomplished without difficulty in all cases. A literature review was performed which comprises case reports of one hundred and twenty-eight patients. Most were asymptomatic, but when symptoms did occur, they could be disabling, such as stroke, myocardial infarction and sudden death. Transthoracic and transesophageal echocardiography has greatly enhanced the ability to make this diagnosis in a timely fashion. Papillary fibroelastoma is by far the most common lesion and is amenable to simple surgical excision with minimal morbidity and mortality. Recurrence has not been reported.

摘要

心脏瓣膜肿瘤罕见,但可能有显著的临床表现。我们报告三例经手术切除成功治疗的二尖瓣肿瘤。三例患者中有两例出现神经系统症状,通过超声心动图发现了瓣膜病变。所有病例均顺利完成了保留正常瓣膜组织和功能的手术切除。进行了文献综述,其中包括128例患者的病例报告。大多数患者无症状,但出现症状时可能会导致残疾,如中风、心肌梗死和猝死。经胸和经食管超声心动图大大提高了及时做出该诊断的能力。乳头状纤维弹性瘤是迄今为止最常见的病变,适合进行简单的手术切除,发病率和死亡率极低。尚未有复发的报道。

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