Mastropasqua L, Verrotti A, Lobefalo L, Chiarelli F, Verdesca G, Morgese G
Department of Pediatrics, University G. D Annunzio, Chieti, Italy.
Acta Ophthalmol Scand. 1995 Apr;73(2):125-8. doi: 10.1111/j.1600-0420.1995.tb00651.x.
The effects of diabetes on retinal function before the onset of clinically detectable retinopathy have been investigated with several methods. Our aim is to evaluate the usefulness of computerized perimetry in early diagnosis of retinal sensitivity impairment in lack of fluorescein angiographic signs of diabetic retinopathy. Seventy diabetic children and adolescents, 39 normoalbuminuric and 31 microalbuminuric patients, and 70 normal subjects were investigated with static computerized perimetry. Normoalbuminuric patients showed functional parameters similar to those of controls, while microalbuminuric patients had a significant reduction of mid-peripheral light sensitivity in comparison with both normoalbuminuric children and controls. Our data suggest that an impaired light sensitivity, in mid-periphery of the visual field, is present in diabetic patients with persistent microalbuminuria.
已经用多种方法研究了糖尿病在临床可检测性视网膜病变发作之前对视网膜功能的影响。我们的目的是评估在缺乏糖尿病视网膜病变荧光素血管造影征象的情况下，计算机视野检查法在早期诊断视网膜敏感性损害中的实用性。对70名糖尿病儿童和青少年（39名正常白蛋白尿患者和31名微量白蛋白尿患者）以及70名正常受试者进行了静态计算机视野检查。正常白蛋白尿患者的功能参数与对照组相似，而微量白蛋白尿患者与正常白蛋白尿儿童和对照组相比，中周边光敏感度显著降低。我们的数据表明，持续性微量白蛋白尿的糖尿病患者存在视野中周边光敏感度受损的情况。
