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12-O-十四烷酰佛波醇-13-乙酸酯的6β-7β-环氧化物对体外辐射转化的影响

Effects of the 6 beta-7 beta-epoxide of 12-O-tetradecanoyl-phorbol-13-acetate on radiation transformation in vitro.

作者信息

Kennedy A R

机构信息

Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

出版信息

Cancer Lett. 1995 Aug 16;95(1-2):7-9. doi: 10.1016/0304-3835(95)03854-p.

Abstract

Experiments were performed to compare the abilities of 12-O-tetradecanoyl-phorbol-12-acetate (TPA), croton oil and TPA-6 beta-7 beta-epoxide to enhance radiation transformation in vitro. Both croton oil and TPA-6 beta-7 beta-epoxide were more powerful than TPA in the ability to promote radiation transformation in vitro.

摘要

进行实验以比较12-氧十四烷酰佛波醇-12-乙酸酯(TPA)、巴豆油和TPA-6β-7β-环氧化物在体外增强辐射转化的能力。巴豆油和TPA-6β-7β-环氧化物在体外促进辐射转化的能力上比TPA更强。

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