Truccone N J, Spotnitz H M, Gersony W M, Dell R, Bowman F O, Malm J R
J Thorac Cardiovasc Surg. 1976 Mar;71(3):410-4.
Green dye measurements of cardiac index (in liters per minute per square meter) were compared in 32 infants and 58 children, 6 and 24 hours after normothermic cardiopulmonary bypass. Cardiac index was significantly lower in infants under one year of age, as compared to older infants and children. This parameter was also lower in patients with total anomalous pulmonary venous drainage, truncus arteriosus, and tetralogy of Fallot. Five infants who died had 6-hour cardiac index determinations of 2.0 L./min./sq. M. Only 2 of 27 survivors had cardiac indices below this level. Simultaneously recorded heart rate and central venous pressure did not correlate with cardiac index. Systolic blood pressure was significantly lower in infants in whom the cardiac index was less then 2.0 L./min./sq. M. (p less than 0.01). However, in individual situations, determination of systemic blood pressure lacked specificity in predicting outcome. Measurements of cardiac index are helpful in the management of infants and children following intracardiac repair by (1) assessing the hemodynamic status, (2) providing a useful indication of the cardiocirculatory effects of therapeutic interventions, and (3) predicting outcome.
在32例婴儿和58例儿童常温体外循环后6小时和24小时，对心脏指数（升/分钟/平方米）的绿色染料测量值进行了比较。与较大的婴儿和儿童相比，一岁以下婴儿的心脏指数显著较低。在完全性肺静脉异位引流、永存动脉干和法洛四联症患者中，该参数也较低。5例死亡婴儿的6小时心脏指数测定值为2.0升/分钟/平方米。27例幸存者中只有2例心脏指数低于此水平。同时记录的心率和中心静脉压与心脏指数无关。心脏指数低于2.0升/分钟/平方米的婴儿收缩压显著较低（p<0.01）。然而，在个别情况下，测定体循环血压在预测预后方面缺乏特异性。心脏指数的测量有助于心脏内修复术后婴儿和儿童的管理，方法包括：（1）评估血流动力学状态；（2）为治疗干预的心脏循环效应提供有用指标；（3）预测预后。
