Schmidt-Habelmann P, Gams E, Sauer U, Kunkel R, Meisner H, Struck E, Sebening F
Herz. 1978 Feb;3(1):55-61.
Between April 1974 and September 1977, 368 infants underwent surgery at the German Heart Center. 287 were less than 1 year of age, and 81 were between the ages of one and two years. In 90 patients (= 24.4%) surgery was necessary because of cyanotic lesions. Within this group corrective procedures were performed in 36 infants during the first year of life, and in 33 during the second year of life, while palliative measures were carried out in these age groups in 15 and 6 infants, respectively. Urgent corrective surgery is indicated as a life-saving measure in neonates with total anomalous pulmonary venous connection (TAPVC) since this lesion is not amenable to either medical nor palliative interventions. Of 10 neonates and young infants who underwent corrective surgery for TAPVC, 3 died during the early post-operative period and 1 subsequently. Balloon atrial septostomy palliatively employed for transposition of the great arteries (TGA) may render only temporary improvement in the clinical status of young infants. In these infants, more favourable results can be achieved through early, functionally-corrective surgery (Mustard-Brom procedure). In 7 infants who underwent correction of TGA during the first year of life there was 1 post-operative death. There was no post-operative mortality in 18 infants whose age at the time of operation was between 1 and 2 years. In the presence of TGA combined with ventricular septal defect there were 3 deaths in 8 infants operated on during the first year of life and none in the 3 who underwent surgery during the second year of life. In the same age groups, early correction of tetralogy of Fallot (TOF) was performed in 11 infants (with 2 deaths) and in 10 infants (with one death), respectively. Thus, in the absence of preclusive, complex anomalies, early surgical correction of congenital cyanotic lesions in young infants consistently yields results superior to that of palliation or two-stage procedures.
1974年4月至1977年9月期间,368名婴儿在德国心脏中心接受了手术。其中287名年龄小于1岁,81名年龄在1至2岁之间。90名患者(占24.4%)因青紫性病变而需要进行手术。在这组患者中,36名婴儿在出生后第一年内接受了矫正手术,33名在出生后第二年内接受了矫正手术,而在这些年龄组中,分别有15名和6名婴儿接受了姑息治疗。对于完全性肺静脉异位连接(TAPVC)的新生儿,紧急矫正手术被视为一种挽救生命的措施,因为这种病变既不能通过药物治疗,也不能通过姑息性干预来解决。在接受TAPVC矫正手术的10名新生儿和婴儿中,3名在术后早期死亡,1名随后死亡。用于大动脉转位(TGA)的球囊房间隔造口术只能暂时改善婴儿的临床状况。对于这些婴儿,通过早期的功能性矫正手术(Mustard-Brom手术)可以取得更理想的效果。7名在出生后第一年内接受TGA矫正手术的婴儿中有1名术后死亡。18名手术时年龄在1至2岁之间的婴儿没有术后死亡病例。在TGA合并室间隔缺损的情况下,8名在出生后第一年内接受手术的婴儿中有3名死亡,而在出生后第二年内接受手术的3名婴儿中没有死亡病例。在同一年龄组中,分别有11名婴儿(2例死亡)和10名婴儿(1例死亡)接受了法洛四联症(TOF)的早期矫正手术。因此,在没有排除性复杂畸形的情况下,对婴儿先天性青紫性病变进行早期手术矫正的效果始终优于姑息治疗或两阶段手术。