Bowie E J, Fass D N, Olson J D, Owen C A
Mayo Clin Proc. 1976 Jan;51(1):35-41.
We have examined nine patients with presumed von Willebrand's disease who present the spectrum of that disorder. Two had findings that would be accepted generally as diagnostic of von Willebrand's disease, and seven had variations of the usual pattern. The commonest variation was the combination of borderline and variable levels of coagulant Factor VIII, commensurate levels of Factor VIII-related antigen, and low levels of ristocetin-Willebrand factor.
我们检查了9名疑似患血管性血友病的患者，这些患者呈现出该病症的一系列症状。其中两名患者的检查结果通常可被认定为血管性血友病的诊断依据，另外七名患者则有不同于常见模式的情况。最常见的差异是凝血因子VIII水平处于临界值且不稳定、VIII相关抗原水平相当，以及瑞斯托菌素-血管性血友病因子水平较低。
