Ma Z, Li H, Gao S
First Hospital of Beijing Medical University.
Zhonghua Wai Ke Za Zhi. 1995 Feb;33(2):82-5.
Limb-salvage surgery plays an important role in the treatment of osteosarcoma. From 1974 to 1993, 104 patients with osteosarcoma were treated in our department. Sixty of them were treated with limb-salvage procedures. In fourty-four patients of stage II B receiving adjuvant chemotherapy, the five-year survival rate was 46.69%. The overall local recurrence rate was 15%. The infection rate was 12.9%, and mechanical complication occurred in 14.8% of the patients. The functional result was generally good. Improved concepts of en bloc resection and better reconstructive techniques suggest that limb-salvage procedures are not only possible but can provide excellent functional result in patients with osteosarcoma. Further work must be directed to reducing local recurrence and improving reconstructive techniques.
保肢手术在骨肉瘤治疗中发挥着重要作用。1974年至1993年，我科共治疗了104例骨肉瘤患者。其中60例行保肢手术。在44例接受辅助化疗的II B期患者中，五年生存率为46.69%。总体局部复发率为15%。感染率为12.9%，14.8%的患者发生机械并发症。功能结果总体良好。整块切除概念的改进和更好的重建技术表明，保肢手术不仅可行，而且能为骨肉瘤患者提供优异的功能结果。必须进一步努力降低局部复发率并改进重建技术。
