Wang M, Feng Y, Zhou X
Department of Surgical Oncology, First Affiliated Hospital Zhejiang Medical University, Hangzhou.
Zhonghua Zhong Liu Za Zhi. 1995 Jan;17(1):33-5.
Serum IL-2 and sIL-2R levels were measured with sandwith ELISA assay before and after surgery or transarterial embolization in 19 cases of primary hepatic carcinoma. The results show that pretreatment IL-2 levels of patients were significantly lower and sIL-2R expression was higher than those of normal control. IL-2 levels of patient were increased and sIL-2R expression was decreased after treatment. The results suggest that the changes of IL-2 level and sIL-2R expression may be closely related to treatment, recurrence and prognosis of patients with primary hepatic carcinoma.
采用夹心ELISA法检测了19例原发性肝癌患者手术或经动脉栓塞前后血清白细胞介素-2（IL-2）和可溶性白细胞介素-2受体（sIL-2R）水平。结果显示，患者治疗前IL-2水平显著低于正常对照组，sIL-2R表达高于正常对照组。治疗后患者IL-2水平升高，sIL-2R表达降低。结果提示，IL-2水平和sIL-2R表达的变化可能与原发性肝癌患者的治疗、复发及预后密切相关。
