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[源自肺动脉的支气管源性癌血供研究]

[Investigation of blood supply of bronchogenic carcinoma deriving from pulmonary artery].

作者信息

Zheng R, Dong Y, Zhou K

机构信息

Department of Thoracic Surgery, Zhongshan Hospital of Shanghai Medical University.

出版信息

Zhonghua Zhong Liu Za Zhi. 1995 Jan;17(1):53-5.

PMID:7656791
Abstract

Microfil perfusion technique was used to investigate the blood supply of bronchogenic carcinoma deriving from pulmonary artery on 20 fresh specimens of lung cancer, including 11 squamous carcinoma, 6 adenocarcinoma, 1 alveolar cell carcinoma and 2 undifferentiated carcinoma cases. The results showed that the appearance and quantity of pulmonary blood supply of bronchogenic carcinoma depended on and changed with the site, activity, growth mode as well as the local condition of tumor nodules; pulmonary artery supplied blood to the periphery of the tumor and its innermost part as well; vessels from pulmonary artery in tumor nodules were generally less in number than those in the surrouding normal lung tissues around. The results suggested that the tumor blood supply from pulmonary artery should be evaluated comprehensively and dynamically; during interventional chemotherapy via pulmonary artery, patients should be selected carefully and the catheter for infusion placed in suitable position so as to gain the best therapeutic effect.

摘要

采用微丝灌注技术,对20例新鲜肺癌标本(包括11例鳞癌、6例腺癌、1例肺泡细胞癌和2例未分化癌)进行研究,以探讨源自肺动脉的支气管肺癌的血供情况。结果显示,支气管肺癌肺血供的表现及数量取决于肿瘤结节的部位、活性、生长方式及局部情况,并随其变化;肺动脉不仅为肿瘤周边供血,也为肿瘤最内部供血;肿瘤结节内来自肺动脉的血管数量一般比周围正常肺组织中的少。结果提示,应全面、动态地评估源自肺动脉的肿瘤血供;在经肺动脉介入化疗时,应谨慎选择患者,并将输注导管置于合适位置,以获得最佳治疗效果。

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