Ma S, Lin D, Sun J
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1995 Mar;17(2):149-51.
Form 1959 through to May, 1993, 363 patients with adenocarcinoma of uterine cervix were initially treated which accounted for 2.5% of all initially treated cases of cervical carcinoma. Patients' mean age was 50.5 years. Forty-six percent of the patients were post-menopausal. The main symptom was irregular vaginal and/or discharge. Over 88% of the cases were in stage II and III of the disease. They were treated with radiotherapy alone. The overall 5-year survival rate was 51.8%. The recurrence rate was 17.4% with a mean time to recurrence of 33.3 months. Thirteen patients recurred beyond 5 years. Recurrence was accompanied with lung metastasis in 17 patients and supraclavicular eymph node metastases in 11. Among patients whose tumor recurred the 1- and 2-year survival rate were 35.2% and 19.2% respectively. The most significant prognostic factors were the stage of disease, the size of the tumor and the histologic subtypes
从1959年至1993年5月,363例子宫颈腺癌患者接受了初始治疗,占所有初始治疗宫颈癌病例的2.5%。患者的平均年龄为50.5岁。46%的患者已绝经。主要症状为不规则阴道出血和/或阴道分泌物。超过88%的病例处于疾病的II期和III期。她们仅接受了放射治疗。总体5年生存率为51.8%。复发率为17.4%,平均复发时间为33.3个月。13例患者在5年后复发。17例患者复发伴有肺转移,11例伴有锁骨上淋巴结转移。在肿瘤复发的患者中,1年和2年生存率分别为35.2%和19.2%。最显著的预后因素是疾病分期、肿瘤大小和组织学亚型。