Mao Y, Zhang R, Zhang D
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1995 May;17(3):219-22.
The article reports the results of preoperative small airway function tests among 116 cases of esophageal carcinoma and its relationship with the postoperative airway infection. Among three main parameters reflecting narrowing of small airway, %V25/HT is the most sensitive one, %MMEF comes next, and %FEV1 the least, Eight-eight of 116 cases without any other postoperative complications were enrolled. The morbidity of postoperative airway infection in this group was 62.5%. They were divided into three groups according to %V25/HT: group I with normal small airway function (%V25/HT > 70%, 26 cases), group II with moderately deviated function (%V25/HT 46-70%, 31 cases), group III with severely deviated function (%V25/HT < 45%, 31 cases). The morbidity rate of postoperative airway infection and the average fever period in the three groups were 50%, 51.6%, 83.3% and 60, 74, 108 hours, respectively. The difference between group I and group III, between group II and group III are significant statistically both in the morbidity rate and the fever period of postoperative airway infection. If divided by different modes of operation, the average postoperative fever perioed in intrathoracic and neck anastomosis group was 79 and 105 hours. The difference between the above two groups is remarkable but not significant statistically. The results come to a conclusion that the patients undergoing larger operation and with more severe abnormal small airway function usually have longer and more severe postoperative airway infection.
本文报道了116例食管癌患者术前小气道功能测试结果及其与术后气道感染的关系。在反映小气道狭窄的三个主要参数中,%V25/HT最敏感,%MMEF次之,%FEV1最不敏感。选取116例无其他术后并发症的患者。该组术后气道感染发病率为62.5%。根据%V25/HT将他们分为三组:I组小气道功能正常(%V25/HT>70%,26例),II组功能中度异常(%V25/HT 46 - 70%,31例),III组功能重度异常(%V25/HT<45%,31例)。三组术后气道感染发病率及平均发热时间分别为50%、51.6%、83.3%和60、74、108小时。I组与III组、II组与III组在术后气道感染发病率及发热时间方面差异均有统计学意义。若按不同手术方式划分,胸内吻合组和颈部吻合组术后平均发热时间分别为79小时和105小时。上述两组之间差异显著但无统计学意义。结果表明,接受较大手术且小气道功能异常较严重的患者术后气道感染通常更严重且持续时间更长。