Celenza J L, Grisafi P L, Fink G R
Whitehead Institute for Biomedical Research, Cambridge, Massachusets 02142, USA.
Genes Dev. 1995 Sep 1;9(17):2131-42. doi: 10.1101/gad.9.17.2131.
In plants, the hormone indole-3-acetic acid (IAA) can initiate the developmental program for lateral root formation. We have isolated mutants that have permitted the dissection of this program into initiation and maturation of lateral roots. The alf1-1 mutation causes hyperproliferation of lateral roots, alf4-1 prevents initiation of lateral roots, and alf3-1 is defective in the maturation of lateral roots. The alf3-1 mutant can be rescued by IAA, whereas the alf4-1 mutant is not rescued. Our data suggest a model in which IAA is required for at least two steps in lateral root development: (1) to initiate cell division in the pericycle, and (2) to promote cell division and maintain cell viability in the developing lateral root.
在植物中，激素吲哚 - 3 - 乙酸（IAA）可启动侧根形成的发育程序。我们分离出了一些突变体，这些突变体使我们能够将该程序细分为侧根的起始和成熟过程。alf1 - 1突变导致侧根过度增殖，alf4 - 1阻止侧根起始，而alf3 - 1在侧根成熟方面存在缺陷。alf3 - 1突变体可被IAA拯救，而alf4 - 1突变体则不能被拯救。我们的数据表明了一个模型，其中IAA在侧根发育的至少两个步骤中是必需的：（1）启动中柱鞘中的细胞分裂，以及（2）促进发育中的侧根中的细胞分裂并维持细胞活力。
