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酿酒酵母合子中线粒体DNA分子重组的限制

The restriction of the recombination of mitochondrial DNA molecules in the zygotes of Saccharomyces cerevisiae.

作者信息

Waxman M F

出版信息

Mol Gen Genet. 1975 Dec 9;141(4):285-90. doi: 10.1007/BF00331450.

Abstract

Crosses were made between strains carrying a nuclear control factor (NC) and strains classified with respect to their omega allele (omega+ or omega-). The characteristic asymmetrical transmission was always observed (as was seen) in crosses not involving the omega factor. The analysis of functional recombinants in a cross involving an NC factor has indicated that the absence of the omega effect may be caused by a restriction in the zygote of the recombination of mitochondrial DNA molecules.

摘要

携带核控制因子(NC)的菌株与根据其ω等位基因(ω+或ω-)分类的菌株进行杂交。在不涉及ω因子的杂交中总是观察到特征性的不对称传递(如所见)。对涉及NC因子的杂交中的功能重组体的分析表明,ω效应的缺失可能是由于线粒体DNA分子重组在合子中的限制所致。

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