Bany J, Pfeffer A, Phegan M, Heath A C
AgResearch, Wallaceville Animal Research Centre, Upper Hutt, New Zealand.
Int J Parasitol. 1995 Jun;25(6):765-8. doi: 10.1016/0020-7519(94)00195-t.
Proliferative responses of peripheral blood and prescapular lymph node lymphocytes from 8 B. ovis-infested and 8 naive lambs to concanavalin A (Con A) and soluble antigen of B. ovis were examined in vitro. The numbers of lice and the extent of cockle were also assessed on each lamb. Prescapular lymph node lymphocytes from infested lambs showed significantly higher responses to B. ovis antigen than those from naive lambs. Only a marginal difference was observed between infested and naive lambs in the response of lymphocytes from peripheral blood. Proliferative responses to Con A by prescapular lymph node or blood cells were not significantly different between groups. The results indicated a relationship between the intensity of louse infestation and the proliferative response of prescapular lymph node lymphocytes to B. ovis antigen.
对8只感染绵羊虱的羔羊和8只未感染的羔羊，检测其外周血和肩胛前淋巴结淋巴细胞对刀豆球蛋白A（Con A）和绵羊虱可溶性抗原的体外增殖反应。同时评估每只羔羊身上的虱子数量和皱襞程度。感染羔羊的肩胛前淋巴结淋巴细胞对绵羊虱抗原的反应显著高于未感染羔羊。外周血淋巴细胞反应在感染和未感染羔羊之间仅观察到微小差异。两组间肩胛前淋巴结或血细胞对Con A的增殖反应无显著差异。结果表明虱子感染强度与肩胛前淋巴结淋巴细胞对绵羊虱抗原的增殖反应之间存在关联。
