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Identification of Leishmania species by a specific DNA probe that is conserved only in the maxicircle DNA of human-infective Leishmania parasites.

作者信息

Lee S T, Chiang S C, Singh A K, Liu H Y

机构信息

Division of Infectious Diseases, Academia Sinica, Taipei, Taiwan, Republic of China.

出版信息

J Infect Dis. 1995 Sep;172(3):891-4. doi: 10.1093/infdis/172.3.891.

DOI:10.1093/infdis/172.3.891
PMID:7658091
Abstract

An A + T-rich repeated DNA sequence cloned from maxicircle DNA of Leishmania mexicana amazonensis was found to be conserved in the maxicircles of human-infective Leishmania species but totally absent from non-human-infective ones. Differences in the pattern of distribution of this repeated sequence in the maxicircles of each human-infective Leishmania species potentially allow the development of a sensitive probe to differentiate among these species.

摘要

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