Ho K J
Department of Laboratory Medicine, National Taiwan University, College of Medicine, Taipei.
J Urol. 1995 Oct;154(4):1335-8.
The usefulness of urinary beta-glucuronidase in screening and followup of urinary tract malignancy was tested.
The activity and concentration of urinary beta-glucuronidase were determined in 80 healthy subjects, 113 urology patients with no cancer, and 60 with transitional cell and 23 with renal cell carcinoma. Patients with cancer were followed for 3 to 33 weeks.
The enzyme activity and concentration were significantly greater in the cancer group, including residual tumor or recurrence after therapy, than in the controls with excellent discrimination.
Urinary beta-glucuronidase was indeed useful in screening and followup of urinary tract malignancy.
检测尿β-葡萄糖醛酸酶在尿路恶性肿瘤筛查及随访中的实用性。
测定了80名健康受试者、113名无癌症的泌尿外科患者、60名移行细胞癌患者和23名肾细胞癌患者尿β-葡萄糖醛酸酶的活性及浓度。对癌症患者进行了3至33周的随访。
癌症组（包括治疗后残留肿瘤或复发者）的酶活性及浓度显著高于对照组，具有良好的鉴别能力。
尿β-葡萄糖醛酸酶在尿路恶性肿瘤的筛查及随访中确实有用。
