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[上气道功能性梗阻]

[Functional obstruction of the upper airway].

作者信息

Montiel G C, Quadrelli S A, Semeniuk G B, Roncoroni A J

机构信息

Instituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires.

出版信息

Medicina (B Aires). 1994;54(5 Pt 1):423-6.

PMID:7658977
Abstract

Laryngeal wheezing caused by emotional stress is usually confused with that caused by bronchospasm and diagnosed as asthma, a well known emotionally influenced entity. Therefore, it is treated with bronchodilators, including corticosteroids, frequently resulting in a iatrogenic Cushing's syndrome. This case report concerns a patient initially considered to have bronchial asthma. Physiological and endoscopic studies allowed us to exclude this disease, as well as any organic obstruction of the upper and lower airway. Flow-volume curve showed that the tidal volume (VT) loop was displaced towards RV during the crisis and the expiratory flow of the VT reached the envelope of the maximal expiratory flow (Fig. 1). Direct larynx observation during fiberoptic bronchoscopy showed not only expiratory but also inspiratory vocal cords adduction. A diagnosis of emotional laryngeal wheezing was made. Excluding asthma, bronchodilators were progressively discontinued. She started to receive alprazolam and psychotherapy and during one year of follow-up she remained symptomless. Two mechanisms may be present in our patient: partial inspiratory adduction of vocal cords and breathing at low lung volume. Despite reported dissimilarities between these two mechanisms both seem to have a similar emotional origin.

摘要

由情绪应激引起的喉部哮鸣通常与支气管痉挛引起的喉部哮鸣相混淆,并被诊断为哮喘,这是一种众所周知的受情绪影响的疾病。因此,患者会接受包括皮质类固醇在内的支气管扩张剂治疗,这常常导致医源性库欣综合征。本病例报告涉及一名最初被认为患有支气管哮喘的患者。生理和内镜检查使我们排除了这种疾病以及上、下气道的任何器质性梗阻。流量-容积曲线显示,发作期间潮气量(VT)环向残气量(RV)偏移,且VT的呼气流量达到最大呼气流量包络线(图1)。纤维支气管镜检查时对喉部的直接观察显示,不仅呼气时而且吸气时声带都会内收。最终诊断为情绪性喉部哮鸣。在排除哮喘后,逐渐停用支气管扩张剂。患者开始接受阿普唑仑和心理治疗,在一年的随访期间她一直没有症状。我们的患者可能存在两种机制:声带部分吸气性内收和低肺容量呼吸。尽管报道显示这两种机制存在差异,但两者似乎都有相似的情绪起源。

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