Rogers P J, Richardson N J, Dernoncourt C
Consumer Sciences Department, Institute of Food Research, Reading, UK.
Neuropsychobiology. 1995;31(4):195-9. doi: 10.1159/000119192.
We agree with the conclusions of a recent article in this journal [James, Neuropsychobiology 1994;30:124-125] that studies on the psychoactive effects of caffeine need to take into account the possibility that the results obtained might represent merely the reversal of deleterious effects of caffeine deprivation rather than an actual net benefit due to caffeine use. However, in a review of recent studies we find no unequivocal evidence of impaired psychomotor performance associated with caffeine withdrawal. This is in contrast to a clear deterioration of mood which occurs even after overnight caffeine deprivation. We concluded that current evidence points to true performance-enhancing effects of caffeine, although the extent of these and the conditions under which caffeine is most effective have yet to be fully determined. At the same time, the existence of significant detrimental effects of caffeine deprivation on psychomotor performance has not been ruled out.
我们认同该期刊近期一篇文章[詹姆斯，《神经精神生物学》1994年；30:124 - 125]的结论，即关于咖啡因精神活性作用的研究需要考虑到这样一种可能性：所获得的结果可能仅仅代表了咖啡因戒断有害影响的逆转，而非因使用咖啡因产生的实际净益处。然而，在对近期研究的综述中，我们未发现与咖啡因戒断相关的明确证据表明精神运动表现受损。这与即使经过一夜的咖啡因戒断后情绪明显恶化形成对比。我们得出结论，当前证据指向咖啡因具有真正的增强表现的作用，尽管这些作用的程度以及咖啡因最有效的条件尚未完全确定。与此同时，咖啡因戒断对精神运动表现产生显著有害影响的可能性也未被排除。
