Hibbert M, Lannigan A, Raven J, Landau L, Phelan P
Department of Thoracic Medicine, University of Melbourne, Victoria, Australia.
Pediatr Pulmonol. 1995 Feb;19(2):129-34. doi: 10.1002/ppul.1950190208.
Annual measurements of lung volumes and forced expiratory flows were made in 281 boys and girls from 8 to 12 years and in another cohort of 287 from 12 to 20 years to measure longitudinal lung growth. Gender differences in growth of lung function were documented, with girls generating greater volume-standardized maximal expiratory flows until age 18.5 years. Beyond that age boys generated higher expiratory flows in proportion to total lung capacity (TLC). There was a time lag of up to 1 year between the age of peak growth velocity in lung volume and peak growth velocity in height. Age at peak growth in flow lagged another year behind that in volume. This was noted more in boys than girls. Dysanaptic lung growth was found with differing rates of growth of maximal expiratory flow compared with TLC or vital capacity (VC).
对281名8至12岁的男孩和女孩以及另一组287名12至20岁的人群进行了肺容积和用力呼气流量的年度测量，以评估肺的纵向生长情况。记录了肺功能生长的性别差异，在18.5岁之前，女孩的容积标准化最大呼气流量更大。超过该年龄后，男孩相对于总肺容量（TLC）产生更高的呼气流量。肺容积峰值生长速度的年龄与身高峰值生长速度之间存在长达1年的时间滞后。流量峰值生长的年龄比容积峰值生长的年龄再滞后1年。这在男孩中比女孩中更为明显。发现最大呼气流量与TLC或肺活量（VC）的生长速率不同，存在肺发育不同步的情况。
