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大肠杆菌30S核糖体蛋白与50S亚基之间的相互作用。

Interactions between 30s ribosomal proteins and 50s subunits of Escherichia coli.

作者信息

Jenness D, Bruce J, Schaup H W

出版信息

Nucleic Acids Res. 1976 Jan;3(1):1-10. doi: 10.1093/nar/3.1.1.

Abstract

The interaction between ribosomal proteins of the 30s subunit with intact 50s subunits was investigated. Experiments with mixtures of total 30s proteins indicated that several 30s proteins including protein s4 would form a stable complex with 50s subunits. Further work with pure s4 indicates that this protein binds stoichiometrically to the 50s subunits, probably through protein-nucleic acid interaction. The possible significance of this interaction is discussed.

摘要

研究了核糖体30S亚基的核糖体蛋白与完整50S亚基之间的相互作用。对30S总蛋白混合物进行的实验表明,包括蛋白s4在内的几种30S蛋白会与50S亚基形成稳定的复合物。对纯s4的进一步研究表明,该蛋白以化学计量方式与50S亚基结合,可能是通过蛋白质-核酸相互作用。讨论了这种相互作用的可能意义。

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