Chuaqui R, Quintana M E, Pérez A, Verni J, Duarte I
Departamento de Anatomía Patológica y Obstetricia y Ginecología, Pontificia Universidad Católica de Chile.
Rev Chil Obstet Ginecol. 1994;59(3):207-13.
The 23 year experience in the Laboratory of Cytology of the Catholic University with the Papanicolaou (PAP) test in pregnant and puerperal women was analyzed. Six hundred eighty eight cases (1,9%) with abnormal smears were collected from a total of 36,524 women. A cytological diagnosis of invasive carcinoma was made in 8 cases, of high-grade intraepithelial neoplasia in 130 cases, of low-grade intraepithelial neoplasia in 292 cases, and a "non conclusive" diagnosis was made in 258 cases. In 6 out of the 8 cases with a cytological diagnosis of invasive carcinoma, this diagnosis was confirmed by histology, and in two other cases the histology showed an in situ carcinoma. Histology was negative in only 3 cases with cytological diagnosis of high-grade intraepithelial neoplasia. The PAP test is also highly effective during pregnancy and puerperium, and its rate of false negative cases is low. We suggest to take advantage of the opportunity the prenatal control offers for taking a PAP test.
分析了天主教大学细胞学实验室在孕妇和产妇中开展巴氏（PAP）试验的23年经验。从总共36524名女性中收集到688例（1.9%）涂片异常病例。细胞学诊断为浸润癌8例，高级别上皮内瘤变130例，低级别上皮内瘤变292例，“非结论性”诊断258例。在细胞学诊断为浸润癌的8例病例中，有6例经组织学证实，另外2例组织学显示为原位癌。在细胞学诊断为高级别上皮内瘤变的病例中，仅3例组织学为阴性。巴氏试验在孕期和产褥期也非常有效，其假阴性率较低。我们建议利用产前检查提供的机会进行巴氏试验。
