Pajtler M, Cugalj B, Milojković M, Makarović Z
Odjel za klinicku citologiju i Odjel za ginekologiju i porodiljstvo, Opće bolnice Osijek.
Jugosl Ginekol Perinatol. 1990 Jan-Apr;30(1-2):15-8.
During a 3-year period, 167 women with an abnormal cytological finding (112-IIIA, 41-IIIB and 14-IV) were followed up cytologically and colposcopically in six weeks' intervals. They were evaluated during pregnancy, vaginal delivery and the puerperal period, and the cytological findings showed no progression of intraepithelial lesions into the invasive ones. Definitive postpartum pathohistological findings in 53 patients showed that 32 had in situ carcinoma, 12 severe and 7 light dysplasias, and 2 benign changes. The possibility of the false negative cytological assessments or invasive cervical carcinoma was excluded. Patholhistological and cytological findings matched in 77% of cases, whereas the degree of the former was lower in 21% and higher in 2% of the patients. In as many as 40.7% of patients the first post-delivery control cytological finding was negative. The reversible nature of these findings is emphasized, as well as the need to follow up these patients for at least one year.
在3年期间，对167名细胞学检查结果异常的女性（112例IIIA期、41例IIIB期和14例IV期）每隔六周进行细胞学和阴道镜随访。在妊娠、阴道分娩及产褥期对她们进行评估，细胞学检查结果显示上皮内病变未进展为浸润性病变。53例患者产后最终的病理组织学检查结果显示，32例为原位癌，12例为重度发育异常，7例为轻度发育异常，2例为良性改变。排除了细胞学评估假阴性或浸润性宫颈癌的可能性。病理组织学和细胞学检查结果在77%的病例中相符，而在21%的患者中前者程度较低，在2%的患者中前者程度较高。多达40.7%的患者产后首次细胞学检查结果为阴性。强调了这些结果的可逆性，以及对这些患者至少随访一年的必要性。
