Martínez M T, Pérez F, Calvillán M, Gutiérrez-López M D, Serrano-Ríos M
Unidad de Diabetes y Lipidos, Hospital Universitario San Carlos, Facultad de Medicina Universidad Complutense, Madrid, España.
Rev Med Chil. 1994 Oct;122(10):1189-95.
Diabetes mellitus is associated with a three to fourfold increased risk for coronary artery disease and diabetic patients frequently have an abnormal plasma lipid profile. Lately, lipoprotein (a) has received attention as an important independent risk factor for cardiovascular disease. This lipoprotein is elevated in patients with type II diabetes mellitus and there may be an association between the metabolic control of these subjects and its levels. In this review the main features of lipoprotein (a) and its relationship to the fibrinolytic system and atherosclerosis are reviewed.
糖尿病与冠状动脉疾病风险增加三至四倍相关，糖尿病患者常伴有异常的血浆脂质谱。近来，脂蛋白(a)作为心血管疾病的重要独立危险因素受到关注。在2型糖尿病患者中这种脂蛋白水平升高，并且这些患者的代谢控制与其水平之间可能存在关联。在这篇综述中，将对脂蛋白(a)的主要特征及其与纤溶系统和动脉粥样硬化的关系进行综述。
