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[神经梅毒与人类免疫缺陷病毒(HIV-1)感染。6例病例的经验]

[Neurosyphilis and human immunodeficiency virus (HIV-1)infection. Experience with 6 cases].

作者信息

Silva C, Agar A M, Guzmán M A, Thompson L, Sepúlveda C

机构信息

Departamento de Neurología-Neurocirugía, Facultad de Medicina, Universidad de Chile, Hospital José Joaquín Aguirre, Santiago.

出版信息

Rev Med Chil. 1994 Dec;122(12):1393-7.

PMID:7659914
Abstract

HIV infected population has a higher incidence of syphilis, being this an independent risk factor for HIV infection. We report 88 HIV infected patients seen during the last three years. Fourteen (16%) had reactive serum VDRL and FTA-ABS and neurosyphilis was diagnosed in six (6.8%). Three had a treponemal uveitis-retinitis, one a meningovascular syphilis and one a secondary syphilis with meningeal and otological involvement. Patients were treated with penicillin 20 million UI/day for 14 days with good clinical and laboratory response and CSF normalization in those subjected to a second lumbar puncture. It is concluded that neurosyphilis must be considered in the differential diagnosis of neurological complications of HIV infections.

摘要

艾滋病毒感染人群梅毒发病率较高,这是艾滋病毒感染的一个独立危险因素。我们报告了过去三年中诊治的88例艾滋病毒感染患者。其中14例(16%)血清性病研究实验室玻片试验(VDRL)和荧光密螺旋体抗体吸收试验(FTA-ABS)呈阳性,6例(6.8%)被诊断为神经梅毒。3例患有密螺旋体性葡萄膜炎-视网膜炎,1例患有脑膜血管梅毒,1例患有累及脑膜和耳部的二期梅毒。患者接受每日2000万单位青霉素治疗,持续14天,临床和实验室反应良好,接受第二次腰椎穿刺的患者脑脊液恢复正常。结论是,在艾滋病毒感染神经并发症的鉴别诊断中必须考虑神经梅毒。

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