Peruzović M, Kniewald J, Capkun V, Milković K
Department of Biology, Medical Faculty University of Zagreb, Croatia.
Acta Physiol Hung. 1995;83(1):79-89.
The influence of the herbicide atrazine on the Fischer rat and their offspring was investigated. Six 120 mg doses of atrazine in paraffin oil per kg body weight were applied every 48 hours to the females in Group A. The females in the control group, Group C, received paraffin oil only. By the end of the intubation period the rats in Group A weighed less than those in Group C. Atrazine did not affect the estrus cycle, gestation and delivery, litter size and pup survival. Adult female offspring of Group A displayed increased activity in the activity cage and the male offspring avoided more electric shocks during the shuttle box acquisition trials. In addition Group A offspring had shorter latency time during extinction trials than Group C offspring.
研究了除草剂阿特拉津对费希尔大鼠及其后代的影响。每48小时给A组雌性大鼠按每千克体重6剂、每剂120毫克的阿特拉津溶于石蜡油中进行灌胃。对照组C组的雌性大鼠只接受石蜡油。在灌胃期结束时，A组大鼠的体重低于C组大鼠。阿特拉津不影响发情周期、妊娠和分娩、窝仔数和幼崽存活率。A组成年雌性后代在活动笼中的活动增加，并且在穿梭箱习得试验中，雄性后代躲避更多电击。此外，在消退试验中，A组后代的潜伏期比C组后代短。
