Bayazit M, Göl M K, Battaloglu B, Tokmakoglu H, Tasdemir O, Bayazit K
Türkiye Yüksek Ihtisas Hastanesi, Cardiovascular Surgery Clinic, Ankara, Turkey.
Am J Surg. 1995 Sep;170(3):246-50. doi: 10.1016/s0002-9610(05)80008-x.
As cardiac complications constitute the principal cause of early and late morbidity and mortality after the surgical treatment of abdominal aortic aneurysm (AAA), a prospective study was planned to evaluate the effects of revascularization of coronary arteries on survival after AAA repair during early and long-term follow-up periods.
A total of 125 patients underwent elective repair of AAA between 1986 and 1994. Coronary arteriography was performed in all cases. All cases with critical left anterior descending artery (LAD) lesions underwent a coronary artery bypass operation either simultaneously or shortly before AAA repair. In addition, percutaneous transluminal coronary angioplasty (PTCA) was performed for symptomatic and critical stenosis of arteries other than the LADs, or if noncritical but symptomatic stenosis of the LADs existed. Early and late follow-up data were obtained for all cases, and late-term cumulative survival rates were calculated.
Coronary artery lesions were found in 66 (53%) cases. In 24 cases, AAA repairs were performed 2.3 (mean) months after coronary artery bypass grafting (CABG), whereas in 4 cases both procedures were performed simultaneously. PTCA was performed in 4 cases 3 to 4 days prior to the abdominal surgery. Even though the coronary artery lesions were found inoperable in 7 cases, these patients underwent repair of AAA because of rapidly expanding and painful aneurysms. Early mortality rate was 4% (5 cases), in which 3 of these were from the group inoperable for CABG. A mean follow-up of 3.17 years (3 to 87 months) was achieved for all discharged patients. Cumulative survival rates for 6 months and 1, 2, 3, and 6 years were 99%, 99%, 95%, 93%, and 89%, respectively.
The results of this study emphasize the importance of coronary artery revascularization for early, and especially for late, survival after AAA repair.
由于心脏并发症是腹主动脉瘤(AAA)手术治疗后早期和晚期发病及死亡的主要原因,因此计划进行一项前瞻性研究,以评估冠状动脉血运重建对AAA修复术后早期和长期随访期间生存率的影响。
1986年至1994年间,共有125例患者接受了AAA择期修复术。所有病例均进行了冠状动脉造影。所有左前降支(LAD)严重病变的病例均在AAA修复术同时或术前不久接受了冠状动脉搭桥手术。此外,对于LAD以外动脉的有症状和严重狭窄,或LAD存在非严重但有症状的狭窄,进行了经皮腔内冠状动脉成形术(PTCA)。获取了所有病例的早期和晚期随访数据,并计算了晚期累积生存率。
66例(53%)发现冠状动脉病变。24例在冠状动脉搭桥术(CABG)后2.3(平均)个月进行了AAA修复,4例同时进行了这两种手术。4例在腹部手术前3至4天进行了PTCA。尽管7例患者的冠状动脉病变无法手术,但由于动脉瘤迅速扩大且疼痛,这些患者仍接受了AAA修复。早期死亡率为4%(5例),其中3例来自无法进行CABG的组。所有出院患者的平均随访时间为3.17年(3至87个月)。6个月、1年、2年、3年和6年的累积生存率分别为99%、99%、95%、93%和89%。
本研究结果强调了冠状动脉血运重建对AAA修复术后早期,尤其是晚期生存的重要性。