Kadioglu A, Erdogru T, Tellaloglu S
Department of Urology, University of Istanbul, Istanbul Faculty of Medicine, Turkey.
Arch Esp Urol. 1995 Jul-Aug;48(6):654-8.
Color Doppler ultrasonography is a useful method in the evaluation of small vessels and vascular anatomy and in demonstrating dynamic changes of blood flow. The detrimental effects of different risk factors of erectile dysfunction such as diabetes mellitus, hypertension, hypercholesterolemia on the penile arterial system were investigated.
180 patients with erectile dysfunction underwent functional evaluation of the arterial system by combined intracavernous injection of 60 mg papaverine and stimulation test and color Doppler ultrasonography.
There were 64 patients (35.55%) whose vascular findings were normal. A total of 36 patients (20.00%) had arterial insufficiency and 42 patients (23.33%) had mixed-arteriogenic-venogenic impotence. Combination of hypertension and hypercholesterolemia was found to be more detrimental to the penile arterial system than hypertension alone, the presence of hypertension and diabetes mellitus together, diabetes alone and hypercholesterolemia.
Color Doppler ultrasonography depends on variables such as equipment, operation and software version in the functional evaluation of the penile arterial system. The combination of hypertension and hypercholesterolemia was found to be more detrimental to the penile arterial system. Further studies based on larger patient populations are required in order to determine the effects of erectile dysfunction contributing disease on the penile arterial system.
彩色多普勒超声检查是评估小血管和血管解剖结构以及显示血流动态变化的一种有用方法。本研究调查了勃起功能障碍的不同危险因素，如糖尿病、高血压、高胆固醇血症对阴茎动脉系统的有害影响。
180例勃起功能障碍患者通过海绵体内联合注射60mg罂粟碱及刺激试验和彩色多普勒超声检查对动脉系统进行功能评估。
64例患者（35.55%）血管检查结果正常。共有36例患者（20.00%）存在动脉供血不足，42例患者（23.33%）患有混合性动静脉性阳痿。研究发现，高血压和高胆固醇血症共同存在对阴茎动脉系统的损害比单独高血压、高血压与糖尿病共同存在、单独糖尿病以及高胆固醇血症更为严重。
在阴茎动脉系统功能评估中，彩色多普勒超声检查取决于设备、操作和软件版本等变量。高血压和高胆固醇血症共同存在对阴茎动脉系统的损害更大。为了确定导致勃起功能障碍的疾病对阴茎动脉系统的影响，需要基于更多患者进行进一步研究。
