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[阴茎同位素成像方法学。评估]

[Methodology of penile isotope imaging. Evaluation].

作者信息

Timmermans L

机构信息

Centre Hospitalier de Nivelles.

出版信息

Acta Urol Belg. 1998 Mar;66(1):13-7.

PMID:9611353
Abstract

AIMS

Duplex ultrasonography and pulsed doppler analysis or dynamic infusion cavernosometry and cavernosography are used for functional evaluation of penile arterial or venous dynamics during a pharmacological erection. The accuracy of the echographic investigations is correlated to the investigator experience. Cavernosometry and cavernosography are more invasive technique than the radioisotope erection penogram, which is a reproductive and reliable test.

MATERIAL AND METHODS

We investigate 60 patients. Neurological, psychological and endocrinological etiology are excluded. The technique is described: thyroid is blocked by potassium perchlorate, bloodpool is labelled with Tc99m, a dynamic study is performed over 60 mn with intracavernous injection of PGE1 5g or Papaverine 30 mg at T10mn, ROIS are defined by computer processing, a phalogram curve is provided.

RESULTS

This noninvasive test sorts out arteriogenic, venogenic and psychogenic impotence by a qualitative curve analysis. The quantitative parameters depending on numerous time consuming variables have proved to be of poor clinical use and non significant. We objectivate 20 psychogenic impotence, 27 arteriogenic impotence, 7 venous leakage and 6 mixed (arteriogenic and venogenic) impotence. Statistic evaluation of arteriogenic lesions comparative by doppler technique reveals a sensitivity of 83% and a specificity of 87%. The advantages of the test are; ambulatory, objective, noninvasive and reliable investigation. In the same time, "qualitative" data evaluates the response to a pharmacological induced erection.

CONCLUSIONS

The radioisotope erection penogram is a noninvasive, reproductive and reliable screening test for vasculogenic impotence.

摘要

目的

双功超声检查及脉冲多普勒分析或动态海绵体测压和海绵体造影用于在药物诱导勃起期间评估阴茎动脉或静脉动力学的功能。超声检查的准确性与检查者的经验相关。海绵体测压和海绵体造影比放射性同位素勃起造影更具侵入性,而放射性同位素勃起造影是一种重复性好且可靠的检查。

材料与方法

我们对60例患者进行了研究。排除神经、心理和内分泌病因。描述该技术如下:用高氯酸钾阻断甲状腺,用Tc99m标记血池,在T10分钟经海绵体内注射5μg前列腺素E1或30mg罂粟碱后进行60分钟的动态研究,通过计算机处理定义感兴趣区(ROI),提供阴茎造影曲线。

结果

这项非侵入性检查通过定性曲线分析区分动脉性、静脉性和心因性阳痿。依赖于众多耗时变量的定量参数已证明临床应用价值不大且无统计学意义。我们确定了20例心因性阳痿、27例动脉性阳痿、7例静脉漏和6例混合性(动脉性和静脉性)阳痿。通过多普勒技术对动脉性病变进行统计学评估显示,敏感性为83%,特异性为87%。该检查的优点是:可门诊进行、客观、非侵入性且可靠。同时,“定性”数据评估对药物诱导勃起的反应。

结论

放射性同位素勃起造影是一种用于血管性阳痿的非侵入性、重复性好且可靠的筛查检查。

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Acta Urol Belg. 1998 Mar;66(1):13-7.
2
Diagnostic value of the radioisotope erection penogram for vasculogenic impotence.
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Int J Impot Res. 1999 Feb;11(1):47-51. doi: 10.1038/sj.ijir.3900369.