Gnehm H E, Waldvogel F A
Schweiz Med Wochenschr. 1975 Jun 21;105(25):815-9.
Two weeks after leaving Nigeria for temperate zones and a few hours after giving birth to twins, a nigerian mother suffered an acute attack of malaria due to Plasmodium falciparum accompanied by cerebral, renal and hematolgical complications. Both infants were apparently healthy at birth, and no parasites were found on peripheral blood smears. Both placentas were macroscopically normal. At two months of age the second infant, a boy, developed non-febrile hemolytic anemia due to Plasmodium falciparum. The clinical picture and pathogenic mechanisms of perinatal malaria are discussed. Possible protection of the twin sister by partial glucose-6-phosphate dehydrogenase deficiency is considered.
一名尼日利亚母亲在前往温带地区两周后，生下双胞胎几小时后，因恶性疟原虫感染引发了疟疾急性发作，并伴有脑、肾和血液学并发症。两个婴儿出生时显然健康，外周血涂片未发现寄生虫。两个胎盘肉眼观察均正常。两个月大时，第二个婴儿，一名男婴，因恶性疟原虫感染患上了无热溶血性贫血。本文讨论了围产期疟疾的临床表现和致病机制。还考虑了双胞胎姐姐因部分葡萄糖-6-磷酸脱氢酶缺乏可能获得的保护作用。
